This type of quara does not pose any major threat to an experienced player with the right runes and equipment, since its melee attack is relatively weak. Knight: you should wait for them to get to you, and simply use melee with full attack and a shield. When it turns invisible use heavy magic missile or Whirlwind Throw to get it visible again or just wait because the invisibility lasts only 1 turn unless it casts it again. Mages: should use energy based attacks. If it runs away in deep red, shoot it with Heavy Magic Missile or area runes. It's safe to fight two at once, provided you're ready to cast a healing spell. Paladins: should use shield and a throwing weapon as Mantassins are very fast and if you use crossbow or bow it could cause you significant damage.