Not very useful, but try to have one in your backpack if you are in a PvP world because it may help save you from a PK trap. You need to stand next to the item(s) you want to desintegrate. It will desintegrate an entire square (it will not desintegrate any dead human body, but it will desintegrate monster bodies). Also, please note it will not work in protection zones. Costs 60 Soul Points per Backpack.
Also note that using this rune will prevent you from entering protection zone for a while (a.k.a. PZ-locked).